Shy, sensitive April is the class virgin, torn between an illicit flirtation with her soccer coach Mr. B and an unrequited crush on sweet stoner Teddy. Emily, meanwhile, offers sexual favors to every boy to cross her path - including both Teddy and his best friend Fred, a life wire without filters or boundaries. As one high school party bleeds into the next - and April and Teddy struggle to admit their mutual affection - Fred's escalating recklessness starts to spiral into chaos.

Jimmy's best friend Sammy has died of leukemia, leaving behind one final wish: ensure his body is buried in his favorite football jersey. Jimmy and his friends, including his ex-friend Dan, his little brother Lump, and his crush Kate join the adventure of a lifetime as they spend one unforgettable night fulfilling their friend's final request.